BDBM50420192 CHEMBL2074851

SMILES CC[n+]1c(CC2C=C(C)N=C(N2C)c2ccccc2)ccc2ccccc12

InChI Key InChIKey=WNJQWMVHCPGIAR-UHFFFAOYSA-N

Data  4 KI  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50420192   

TargetSolute carrier family 22 member 2(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 1.50E+4nMAssay Description:TP_TRANSPORTER: inhibition of Amantadine uptake (in the presence of bicarbonate) (Amantadine: 10 uM) in OCT2-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 450nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (in the absence of bicarbonate) (TEA: 20 uM) in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 400nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (in the presence of bicarbonate) (TEA: 20 uM) in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 1.20E+3nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (in the absence of bicarbonate) (TEA: 20 uM) in OCT2-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 8.90E+4nMAssay Description:TP_TRANSPORTER: inhibition of Amantadine uptake (in the presence of bicarbonate) (Amantadine: 10 uM) in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 2.00E+5nMAssay Description:TP_TRANSPORTER: inhibition of Amantadine uptake (in the presence of bicarbonate) (Amantadine: 10 uM) in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 2.00E+5nMAssay Description:TP_TRANSPORTER: inhibition of Amantadine uptake (in the presence of bicarbonate) (Amantadine: 10 uM) in OCT2-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 1.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (in the presence of bicarbonate) (TEA: 20 uM) in OCT2-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 1.76E+3nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.2 uM) in OCT3-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 510nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataIC50: 2.56E+3nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataKi:  130nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Anatomisches Institut Der Bayerischen Julius-Maximilians-Universit£T

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataKi:  210nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataKi:  670nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Manitoba

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)
Affinity DataKi:  861nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (apical to cell) in OCT2-expressing NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed