BDBM50420082 CHEMBL2047516

SMILES CC(C)Sc1ccc(cc1F)C(=O)Nc1ccc(Cl)nc1

InChI Key InChIKey=HEHMLFODZYNREB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420082   

TargetPotassium voltage-gated channel subfamily KQT member 2/3(Human)
TBA

Curated by ChEMBL

LigandBDBM50420082(CHEMBL2047516)Copy SMILESCopy InChI

Affinity DataEC50:  110nMAssay Description:Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetPotassium voltage-gated channel subfamily E/KQT member 1(Human)
TBA

Curated by ChEMBL

LigandBDBM50420082(CHEMBL2047516)Copy SMILESCopy InChI

Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL