BDBM50419917 CHEMBL1956867

SMILES Cc1cc(C)c2cccc(OCc3c(Cl)ccc(c3Cl)S(=O)(=O)NC3(CCOCC3)C(=O)N3CC[N+]4(CC3)CC[N+](C)(C)CC4)c2n1

InChI Key InChIKey=OYRVSOVPWBWKJP-UHFFFAOYSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50419917   

TargetB2 bradykinin receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50419917(CHEMBL1956867)
Affinity DataKd:  5.01nMAssay Description:Antagonist activity at human bradykinin B2 receptor expressed in dhfr-deficient CHO cells assessed as inhibition of bradykinin-induced inositol monop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50419917(CHEMBL1956867)
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]-Bradykinin from human bradykinin B2 receptor expressed in CHO cells membrane after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50419917(CHEMBL1956867)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H][desArg9]Lys-Bradykinin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed