BDBM50419621 CHEMBL1940314

SMILES O[C@]1(CN2CCC1CC2)C#Cc1ccc(Oc2ccc(cc2)C(=O)NC2CCS(=O)(=O)CC2)cc1

InChI Key InChIKey=OMQWCWIEQOEJBD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50419621   

Target72 kDa type IV collagenase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419621(CHEMBL1940314)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP2 using Mca-Pro-cyclohexyl-Ala-Gly-Nva-His-Ala- Dap(Dnp)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419621(CHEMBL1940314)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-cyclohexyl-Ala-Gly-Nva-His-Ala- Dap(Dnp)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419621(CHEMBL1940314)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP9 using Mca-Pro-cyclohexyl-Ala-Gly-Nva-His-Ala- Dap(Dnp)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419621(CHEMBL1940314)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP14 using Mca-Pro-cyclohexyl-Ala-Gly-Nva-His-Ala- Dap(Dnp)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419621(CHEMBL1940314)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP12 using Mca-Pro-cyclohexyl-Ala-Gly-Nva-His-Ala- Dap(Dnp)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed