BDBM50419320 CHEMBL2092734

SMILES F[C@@H]1CN(CCC11OCCN1S(=O)(=O)c1ccccc1)C(=O)Nc1ccccc1

InChI Key InChIKey=JSJWQXSSQJPVPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419320   

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50419320(CHEMBL2092734)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at OX2R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50419320(CHEMBL2092734)
Affinity DataIC50: 280nMAssay Description:Antagonist activity at OX1R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed