BDBM50419263 CHEMBL1835057

SMILES Cc1cccc(Nc2nc(N[C@@H]3CCNC3)ncc2C(N)=O)c1

InChI Key InChIKey=ODRSUVBAJITCIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419263   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419263(CHEMBL1835057)
Affinity DataIC50: 501nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells after 2 hrs by Cy3b-Dofetilide-based fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419263(CHEMBL1835057)
Affinity DataIC50: 25nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed