BDBM50419248 CHEMBL1834756

SMILES Cc1cccc(Nc2nc(OCCN)ncc2C(N)=O)c1

InChI Key InChIKey=WHVGSXCRWGRKGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419248   

TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419248(CHEMBL1834756)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant Flag-6His-Thr-tagged Aurora B assessed as phosphorylation of 5FAM-PKA-tide substrate after 150 mins by fuorescence po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419248(CHEMBL1834756)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed