BDBM50418568 CHEMBL146822

SMILES CN(CCOc1ccc(CC(Nc2ccccc2C(=O)Cc2ccccc2)C(O)=O)cc1)c1nc2ccccc2o1

InChI Key InChIKey=QCXQRVQRFRSCLV-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50418568   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50418568(CHEMBL146822)
Affinity DataEC50:  47nMAssay Description:Ability to promote differentiation of C3H10T1/2 stem cells to adipocytes using lipogenesis assay mediated through activation of Peroxisome proliferat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50418568(CHEMBL146822)
Affinity DataEC50:  29nMAssay Description:Activation of peroxisome proliferator activated receptor gamma measured by induction of 50% of maximum alkaline phosphatase activity, transfection as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50418568(CHEMBL146822)
Affinity DataKi:  3.30nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50418568(CHEMBL146822)
Affinity DataKi:  1.18E+8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed