BDBM50418362 CHEMBL4160963

SMILES CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCN(CC1)C(=S)NC(=O)Cc1ccc(Cl)cc1

InChI Key InChIKey=YVZDPMOQPJVICD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418362   

TargetSmoothened homolog(Mouse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50418362(CHEMBL4160963)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed