BDBM50418101 CHEMBL4169989

SMILES Cc1ccc(NCc2cccn2-c2nnc(s2)N2CCC(CC2)C(=O)NCC(C)(C)O)cc1

InChI Key InChIKey=SUIOHPLKNWRVGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50418101   

TargetSmoothened homolog(Mouse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50418101(CHEMBL4169989)
Affinity DataIC50: 4.27E+3nMAssay Description:Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50418101(CHEMBL4169989)
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed