BDBM50418059 CHEMBL1688969

SMILES C(Cn1cc(CC2CCCCC2)nn1)c1cnc[nH]1

InChI Key InChIKey=KUWPQNYVWRUDNF-UHFFFAOYSA-N

Data  2 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50418059   

TargetHistamine H4 receptor(Human)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50418059(CHEMBL1688969)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human histamine H4 receptor expressed in HEK293 cells assessed by forskolin induced cAMP response element activation by luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50418059(CHEMBL1688969)
Affinity DataEC50:  251nMAssay Description:Agonist activity at human histamine H3 receptor expressed in HEK293 cells assessed by forskolin induced cAMP response element activation by luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50418059(CHEMBL1688969)
Affinity DataEC50:  126nMAssay Description:Agonist activity at histamine H4 receptor (unknown origin) expressed in HEK293T cells harboring CRE-luciferase after 6 hrs by luciferase reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50418059(CHEMBL1688969)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at histamine H4 receptor (unknown origin) expressed in human U2OS cells increase in beta-arrestin2 recruitment after 2 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50418059(CHEMBL1688969)
Affinity DataKi:  75.9nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50418059(CHEMBL1688969)
Affinity DataKi:  776nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed