BDBM50417924 CHEMBL1668502::US8618114, 1.1.3(1)

SMILES CSc1nn2c(C)ccnc2c1S(=O)(=O)c1ccccc1

InChI Key InChIKey=MZLLXENSSNWXKW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50417924   

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50417924(CHEMBL1668502 | US8618114, 1.1.3(1))
Affinity DataIC50: 1.11E+3nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2014
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50417924(CHEMBL1668502 | US8618114, 1.1.3(1))
Affinity DataIC50: 40nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2014
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50417924(CHEMBL1668502 | US8618114, 1.1.3(1))
Affinity DataKi:  22.9nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed