BDBM50417919 CHEMBL1668591::US8829009, 1.1(5)

SMILES CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1cccc(F)c1

InChI Key InChIKey=QSPVQFNITBFSRY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417919   

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50417919(CHEMBL1668591 | US8829009, 1.1(5))
Affinity DataIC50: 5nMAssay Description:Determination of antagonistic activity of compounds of general formula 1 towards 5-HT6 receptors. Compounds of general formula 1 were tested for thei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50417919(CHEMBL1668591 | US8829009, 1.1(5))
Affinity DataKi:  0.501nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed