BDBM50417910 CHEMBL1668577::US8552005, 1.1(17)

SMILES COc1ccc(cc1)S(=O)(=O)c1c(SC)nn2c(C)cc(C)nc12

InChI Key InChIKey=WNRRPUVNHOWZFD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417910   

Target5-hydroxytryptamine receptor 6(Human)
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50417910(CHEMBL1668577 | US8552005, 1.1(17))
Affinity DataIC50: 440nMAssay Description:Functional assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 6(Human)
Avincuro Pharmaceuticals

US Patent
LigandPNGBDBM50417910(CHEMBL1668577 | US8552005, 1.1(17))
Affinity DataKi:  37.1nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed