BDBM50417900 CHEMBL1668090

SMILES C[C@@H](CNc1cc(C)cc2n(ncc12)-c1cccc(c1)C(=O)N(C)[C@H](C)C(N)=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=JXGFNTHVYMEJNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50417900   

TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417900(CHEMBL1668090)
Affinity DataIC50: 31.6nMAssay Description:Displacement of fluorescent-labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417900(CHEMBL1668090)
Affinity DataIC50: 2.51nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417900(CHEMBL1668090)
Affinity DataIC50: 50.1nMAssay Description:Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed