BDBM50417605 CHEMBL1645393

SMILES Cc1noc(C)c1S(=O)(=O)NCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=YXYHXIHEKLZBDJ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50417605   

TargetGlucocorticoid receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50417605(CHEMBL1645393)
Affinity DataEC50:  1.00E+3nMAssay Description:Binding affinity to human recombinant GR by competition ligand binding fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50417605(CHEMBL1645393)
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity to human recombinant PR by competition ligand binding fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50417605(CHEMBL1645393)
Affinity DataIC50: 356nMAssay Description:Displacement of [3H]aldosterone from GST-tagged human mineralocorticoid receptor ligand binding domain after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed