BDBM50415442 CHEMBL598609

SMILES FC(F)(F)c1ccc(nc1)S(=O)(=O)CCNC(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=KSXBJBDPHYBSET-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50415442   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415442(CHEMBL598609)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GW2433 from human PPARalpha receptor by ligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415442(CHEMBL598609)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PPARgamma receptor by ligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415442(CHEMBL598609)
Affinity DataIC50: 200nMAssay Description:Inhibition of human PPARdelta receptor by ligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415442(CHEMBL598609)
Affinity DataIC50: 251nMAssay Description:Antagonist activity at human PPARdelta ligand binding domain-mediated transcriptional activity in CV1 cells by Gal4 chimera reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50415442(CHEMBL598609)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50415442(CHEMBL598609)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed