BDBM50415044 CHEMBL569587

SMILES O=C(Cc1cccc2ccccc12)Nc1cn(cn1)[C@@H]1C[C@@H](C1)NC(=O)c1ccccn1

InChI Key InChIKey=NPXTWLXCVUMFMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50415044   

TargetCyclin-dependent kinase 5 activator 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50415044(CHEMBL569587)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK5/p25 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50415044(CHEMBL569587)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human CDK5/p25 expressed in CHO cells after 2 hrs by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed