BDBM50414972 CHEMBL568296

SMILES CC1Cc2cccc(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccncc3)c2O1

InChI Key InChIKey=JQIOFPJNEBMYKB-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50414972   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50414972(CHEMBL568296)Copy SMILESCopy InChI

Affinity DataIC50: 8.13E+3nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/21/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50414972(CHEMBL568296)Copy SMILESCopy InChI

Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of wild type human ERG expressed in CHOK1 cells by whole-cell plate-based electrophysiologyMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/21/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetC-C chemokine receptor type 8(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50414972(CHEMBL568296)Copy SMILESCopy InChI

Affinity DataIC50: 129nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/21/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL