BDBM50414861 CHEMBL574827

SMILES Clc1cccc(c1)N1CCN(CCCCn2cnc3ccccc3c2=O)CC1

InChI Key InChIKey=XGTCJFHULKEJKG-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50414861   

Target5-hydroxytryptamine receptor 1A(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50414861(CHEMBL574827)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]-5-HT from human 5-HT1A receptor expressed in CHOK1 cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50414861(CHEMBL574827)
Affinity DataKi:  50nMAssay Description:Binding affinity to rat hippocampus 5-HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50414861(CHEMBL574827)
Affinity DataKi:  50.1nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HEK293 cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50414861(CHEMBL574827)
Affinity DataKi:  67.6nMAssay Description:Displacement of [3H]ketanserin from 5-HT2A receptor in Wistar Hannover rat brain cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50414861(CHEMBL574827)
Affinity DataKi:  502nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT7 receptor expressed in CHOK1 cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed