BDBM50414756 CHEMBL569201

SMILES CCOc1ccccc1N1CCN(CC(O)CN2CCC(C2=O)(c2ccccc2)c2ccccc2)CC1

InChI Key InChIKey=XNFQPXDAESFNLR-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414756   

TargetAlpha-1D adrenergic receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50414756(CHEMBL569201)
Affinity DataKd:  55.0nMAssay Description:Antagonist activity at Alpha-1D adrenoceptor in Wistar rat thoracic aorta assessed as inhibition of noradrenaline-induced contraction after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50414756(CHEMBL569201)
Affinity DataKd:  281nMAssay Description:Antagonist activity at Alpha-1B adrenoceptor in guinea pig spleen assessed as inhibition of noradrenaline-induced contraction after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed