BDBM50414633 CHEMBL556436

SMILES O=C(NCC#N)C(Cc1cccc(c1)-c1cccnn1)NC(=O)c1ccccc1

InChI Key InChIKey=BKBPVMYBRCWYHF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50414633   

TargetProcathepsin L(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414633(CHEMBL556436)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414633(CHEMBL556436)
Affinity DataIC50: 63.1nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCathepsin K(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414633(CHEMBL556436)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of cathepsin K assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCathepsin S(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414633(CHEMBL556436)
Affinity DataIC50: 7.94nMAssay Description:Inhibition of cathepsin S assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414633(CHEMBL556436)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human liver cathepsin B assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed