BDBM50414628 CHEMBL551533

SMILES O=C(NCC#N)C(Cc1cccc(c1)-c1cncnc1)NC(=O)c1ccccc1

InChI Key InChIKey=DBVBMQPLQKOZGO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50414628   

TargetProcathepsin L(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414628(CHEMBL551533)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414628(CHEMBL551533)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414628(CHEMBL551533)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human liver cathepsin B assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCathepsin K(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414628(CHEMBL551533)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of cathepsin K assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCathepsin S(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414628(CHEMBL551533)
Affinity DataIC50: 316nMAssay Description:Inhibition of cathepsin S assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed