BDBM50414480 CHEMBL5267562

SMILES CC(C)CN(c1ccccc1F)S(=O)(=O)c1ccc2OC(CC(O)c2c1)C1CCOCC1

InChI Key InChIKey=JFSPFURHWCZMMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414480   

TargetNuclear receptor ROR-gamma(Human)
Jiangsu Carefree Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50414480(CHEMBL5267562)
Affinity DataIC50: 23nMAssay Description:Displacement of BODIPY from APC-labelled human RORgammat LBD incubated for 15 mins by by LANCE detection analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Jiangsu Carefree Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50414480(CHEMBL5267562)
Affinity DataIC50: 190nMAssay Description:Inhibition of RORgammat in human Jurkat cells assessed as inhibition of RORgammat transcriptional activity incubated for 10 mins by luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed