BDBM50414443 CHEMBL549894

SMILES CC(C)N1CCN(CCN2CCN(C2=O)c2cccc(OC(F)(F)F)c2)CC1

InChI Key InChIKey=GNQOCBGVODGUEX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50414443   

TargetD(3) dopamine receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414443(CHEMBL549894)
Affinity DataKi:  3.16nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414443(CHEMBL549894)
Affinity DataKi:  251nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414443(CHEMBL549894)
Affinity DataIC50: 1.58E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed