BDBM50414310 CHEMBL563255

SMILES OCCn1ccc2c(NC(=O)Cc3ccc(c(F)c3)C(F)(F)F)c(Cl)ccc2c1=O

InChI Key InChIKey=ZXOKHTSAKAOOLZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414310   

TargetP2X purinoceptor 7(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414310(CHEMBL563255)
Affinity DataIC50: 6.31nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed