BDBM50413878 CHEMBL453707

SMILES CS(=O)(=O)Nc1ccc(cc1)-c1ccnc2[nH]ccc12

InChI Key InChIKey=UISYHKUAFRQWRK-UHFFFAOYSA-N

Data  2 IC50  1 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50413878   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50413878(CHEMBL453707)Copy SMILESCopy InChI

Affinity DataIC50: 158nMAssay Description:Inhibition of human recombinant IKK2More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/21/2013
Entry Details Article
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TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50413878(CHEMBL453707)Copy SMILESCopy InChI

Affinity DataIC50: 794nMAssay Description:Inhibition of human recombinant IKK1More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/21/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetVenus kinase receptor 2(Blood fluke)
Imperial College London

Curated by ChEMBL

LigandBDBM50413878(CHEMBL453707)Copy SMILESCopy InChI

Affinity DataKd:  7.80E+3nMAssay Description:Binding affinity to Schistosoma mansoni N-terminal His6-tagged full-length VKR2 kinase domain expressed in baculovirus infected Sf9 insect cells in p...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/22/2023
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL