BDBM50413247 CHEMBL472455

SMILES COc1ccc(N(C(C(=O)NC2CCCC2)c2ccccc2F)C(=O)c2ccco2)c(OC)c1

InChI Key InChIKey=QPVXGDQEVHBJSA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50413247   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50413247(CHEMBL472455)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of [Alexa647]C5a from human recombinant C5a receptor expressed in HEK cells by membrane binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50413247(CHEMBL472455)
Affinity DataIC50: 251nMAssay Description:Displacement of [Alexa647]C5a from human recombinant C5a receptor expressed in HEK cells by membrane binding assay in presence of [35S]GTPgammaSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50413247(CHEMBL472455)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at human recombinant C5a receptor in HEK cells assessed as inhibition of C5a-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50413247(CHEMBL472455)
Affinity DataIC50: 79.4nMAssay Description:Displacement of [Alexa647]C5a from human recombinant C5a receptor expressed in HEK cells by whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed