BDBM50412447 CHEMBL380101

SMILES C(N1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1

InChI Key InChIKey=KPTFXOABKWRVBF-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50412447   

TargetAcetylcholinesterase(Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50412447(CHEMBL380101)
Affinity DataIC50: 5.89E+3nMAssay Description:Inhibition of acetylcholinesterase in Wistar rat brain homogenate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50412447(CHEMBL380101)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to histamine H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50412447(CHEMBL380101)
Affinity DataKi:  0.339nMAssay Description:Displacement of [3H]RAMHA from human histamine H3 receptor transfected in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50412447(CHEMBL380101)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]RAMHA from histamine H3 receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50412447(CHEMBL380101)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]RAMHA from histamine H3 receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50412447(CHEMBL380101)
Affinity DataKi:  3.39nMAssay Description:Displacement of [3H]RAMHA from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50412447(CHEMBL380101)
Affinity DataKi:  2.51E+4nMAssay Description:Displacement of [3H]RAMHA from human histamine H4 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed