BDBM50412359 CHEMBL471170

SMILES COc1cc2CCN(CCc3ccc(NC(=O)c4ccccc4)cc3)Cc2cc1OC

InChI Key InChIKey=WQFANMYSSGNEFC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412359   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50412359(CHEMBL471170)Copy SMILESCopy InChI

Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells by Hoechst 33342 assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/21/2013
Entry Details Article
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TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50412359(CHEMBL471170)Copy SMILESCopy InChI

Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of P-glycoprotein-mediated multidrug resistance in adriamycin-resistant human A2780/ADR cells by calcein AM assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/26/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL