BDBM50412225 CHEMBL480789

SMILES CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1

InChI Key InChIKey=ZJOSQPMXIGOIML-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412225   

TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412225(CHEMBL480789)
Affinity DataIC50: 12.6nMAssay Description:Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412225(CHEMBL480789)
Affinity DataKi:  126nMAssay Description:Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed