BDBM50411712 CHEMBL271083

SMILES Cc1ncoc1-c1nnc(SCCCN2CCc3cc4nc(oc4cc3CC2)C(F)(F)C(F)(F)F)n1C

InChI Key InChIKey=DOTHXJXYLNKQOQ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50411712   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411712(CHEMBL271083)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]Dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411712(CHEMBL271083)
Affinity DataKi:  3.16nMAssay Description:Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411712(CHEMBL271083)
Affinity DataKi: >631nMAssay Description:Antagonist activity at dopamine D2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411712(CHEMBL271083)
Affinity DataKi: >2.51E+3nMAssay Description:Antagonist activity at histamine H1 receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed