BDBM50411482 CHEMBL393920

SMILES CCC1(CC(O)(CNc2cccc3ncccc23)C(F)(F)F)CCCc2ccccc12

InChI Key InChIKey=HOGKUWCBDMVMEX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50411482   

TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411482(CHEMBL393920)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by MMTV transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411482(CHEMBL393920)
Affinity DataIC50: 11.2nMAssay Description:Displacement of fluorescent labeled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411482(CHEMBL393920)
Affinity DataIC50: 12.3nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed