BDBM50411475 CHEMBL237496

SMILES CC1(CC(O)(Cc2ccnc3ccccc23)C(F)(F)F)CCCc2ccccc12

InChI Key InChIKey=XULBSIKQABBRCP-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50411475   

TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411475(CHEMBL237496)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by MMTV transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411475(CHEMBL237496)
Affinity DataIC50: 24.0nMAssay Description:Displacement of fluorescent labeled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411475(CHEMBL237496)
Affinity DataIC50: 24nMAssay Description:Displacement of fluorescent labeled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411475(CHEMBL237496)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411475(CHEMBL237496)
Affinity DataEC50:  12.9nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by MMTV transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411475(CHEMBL237496)
Affinity DataIC50: 7.08nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed