BDBM50411415 CHEMBL232599

SMILES c1ccc2c(c1)cccc2C(=O)Nc3c(c4c(s3)CN(CC4)C(=O)CCN5CCCCC5)C#N

InChI Key InChIKey=PRZGSWGFNRYBIP-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50411415   

TargetMitogen-activated protein kinase 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411415(CHEMBL232599)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411415(CHEMBL232599)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human JNK2alpha2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411415(CHEMBL232599)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ERK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411415(CHEMBL232599)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of mitogen-activated protein kinase p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411415(CHEMBL232599)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)