BDBM50410873 CHEBI:65737::CHEMBL105360

SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2)ccc1O

InChI Key InChIKey=HJTVQHVGMGKONQ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50410873   

TargetATP-dependent translocase ABCB1(Human)
National Institute of Pharmaceutical Education and Research-Hyderabad

Curated by ChEMBL
LigandPNGBDBM50410873(CHEMBL105360 | CHEBI:65737)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of P-gp1 efflux in human Flp-In-293 cells using rhodamine as substrate assessed as increase in intracellular accumulation of rhodamine 123...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
National Institute of Pharmaceutical Education and Research-Hyderabad

Curated by ChEMBL
LigandPNGBDBM50410873(CHEMBL105360 | CHEBI:65737)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of P-gp1 efflux in human Flp-In-293 cells using calcein-AM as substrate assessed as increase in intracellular accumulation of calcein-AM p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50410873(CHEMBL105360 | CHEBI:65737)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human MAO-B using benzylamine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Indian Institute of Technology Delhi

Curated by ChEMBL
LigandPNGBDBM50410873(CHEMBL105360 | CHEBI:65737)
Affinity DataIC50: 7.03E+4nMAssay Description:Inhibition of Staphylococcus aureus SrtA using EDANS-Dabcyl as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50410873(CHEMBL105360 | CHEBI:65737)
Affinity DataKi:  910nMAssay Description:Inhibition of human MAO-A assessed as inhibition constant using kynuramine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed