BDBM50410843 CHEMBL5281221

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(C)c(Nc3ccc(cc3)S(=O)(=O)NC(C)(C)C)n2)cc1

InChI Key InChIKey=WSKICYYWJICJCC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50410843   

TargetBromodomain-containing protein 4(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50410843(CHEMBL5281221)
Affinity DataIC50: 130nMAssay Description:Inhibition of His-tagged BRD4 (unknown origin) using biotinylated histone H4 peptide (1 to 21 residues) containing KAc (K5/8/12/16Ac) by chemilumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50410843(CHEMBL5281221)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of JAK2 (unknown origin) by 33P-ATP radiolabeled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50410843(CHEMBL5281221)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of FLT3 (unknown origin) by 33P-ATP radiolabeled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed