BDBM50410842 CHEMBL5273551

SMILES COc1ccc(NC(=O)Nc2ccc(Oc3ccc(cc3)C(=O)c3ncc[nH]3)cc2)cc1

InChI Key InChIKey=IDSBKSNJFXEPRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50410842   

TargetHistone deacetylase 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50410842(CHEMBL5273551)
Affinity DataIC50: 635nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Fluor-de-Lys as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50410842(CHEMBL5273551)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of full length human BRAF V600E mutant using His-tagged full length human MEK1 (K97R) as substrate incubated for 20 mins by [gamma-33P]ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed