BDBM50409631 CHEMBL5279214

SMILES CC(C)(O)c1ccc(cc1)-c1cn2cccc2c(=O)[nH]1

InChI Key InChIKey=WADUGMWGTNMWRD-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50409631   

LigandPNGBDBM50409631(CHEMBL5279214)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of TNKS1 (unknown origin) using biotinylated NAD as substrate assessed as inhibition of autoPARsylation activity incubated for 1 hr by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50409631(CHEMBL5279214)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of TNKS2 (unknown origin) using biotinylated NAD as substrate assessed as inhibition of autoPARsylation activity incubated for 1 hr by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50409631(CHEMBL5279214)
Affinity DataIC50: 920nMAssay Description:Inhibition of PARP-1 (unknown origin) using biotinylated NAD and NAD as substrate assessed as inhibition of auto-PARsylation incubated for 150 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50409631(CHEMBL5279214)
Affinity DataKd:  6nMAssay Description:Binding affinity to recombinant human TNKS1 (1091 to 1327 residues) assessed as dissociation constant by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed