BDBM50409621 CHEMBL5269584

SMILES Cc1ccc2n1cc([nH]c2=O)-c1ccc(cc1)[C@@](C)(O)CO

InChI Key InChIKey=AOMPHWKJTUPEOB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50409621   

LigandPNGBDBM50409621(CHEMBL5269584)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of TNKS1 (unknown origin) using biotinylated NAD as substrate assessed as inhibition of autoPARsylation activity incubated for 1 hr by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM50409621(CHEMBL5269584)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of TNKS2 (unknown origin) using biotinylated NAD as substrate assessed as inhibition of autoPARsylation activity incubated for 1 hr by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50409621(CHEMBL5269584)
Affinity DataIC50: 748nMAssay Description:Inhibition of PARP-1 (unknown origin) using biotinylated NAD and NAD as substrate assessed as inhibition of auto-PARsylation incubated for 150 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed