BDBM50409493 CHEMBL310734

SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC2CC(=O)c3ccccc3C2)CC1

InChI Key InChIKey=WIVGCTVBLDUZMD-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50409493   

Target5-hydroxytryptamine receptor 2A(Rat)
Universidad De Santiago

Curated by ChEMBL
LigandPNGBDBM50409493(CHEMBL310734)
Affinity DataKi:  18nMAssay Description:In vitro ability to displace [3H]ketanserin binding from 5-hydroxytryptamine 2A receptor in rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidad De Santiago

Curated by ChEMBL
LigandPNGBDBM50409493(CHEMBL310734)
Affinity DataKi:  18nMAssay Description:Kinetic inhibition constant evaluated by measuring serotonergic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50409493(CHEMBL310734)
Affinity DataKi:  25nMAssay Description:Compound was evaluated for its affinity (pKi) to inhibit [3H]spiperone binding to the dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50409493(CHEMBL310734)
Affinity DataKi:  25nMAssay Description:In vitro ability to displace [3H]spiperone binding from dopamine receptor D2 in rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50409493(CHEMBL310734)
Affinity DataKi:  56nMAssay Description:Tested for the binding affinity towards 5-HT2 receptor measured by [3H]ketanserin binding to frontal cerebral cortex membranes of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2018
Entry Details

TargetD(1A) dopamine receptor(Rat)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50409493(CHEMBL310734)
Affinity DataKi:  380nMAssay Description:Compound was evaluated for its affinity (pKi) to inhibit [3H]SCH-23390 binding to the dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2014
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50409493(CHEMBL310734)
Affinity DataKi:  380nMAssay Description:In vitro ability to displace [3H]SCH-23390 binding from Dopamine 1 (D1) receptor in rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed