BDBM50409058 CHEMBL5266734

SMILES Nc1nc(cc(-c2ccc(O)c(O)c2)c1C#N)-c1ccc(F)cc1

InChI Key InChIKey=DWZPPBGRCDPFSS-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409058   

TargetInterleukin-4(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50409058(CHEMBL5266734)
Affinity DataKd:  1.80E+3nMAssay Description:Inhibition of IL-4 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInterleukin-4(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50409058(CHEMBL5266734)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of IL-4 (unknown origin) in human THP-1 cells assessed as inhibition of STAT6 phosphorylation by HEK-Blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed