BDBM50409033 CHEMBL2112735

SMILES C[C@]12CC[C@H]3[C@@H](CCC4=C[C@@H](O)CC[C@]34C)C1CCC2=CCN=O

InChI Key InChIKey=FGUJMLVLDVILIG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50409033   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409033(CHEMBL2112735)
Affinity DataIC50: 140nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 rat enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409033(CHEMBL2112735)
Affinity DataIC50: 430nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type 2 from human BPH tissue at 210 nM of testosteroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409033(CHEMBL2112735)
Affinity DataIC50: 180nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed