BDBM50409032 CHEMBL2112737

SMILES CC(N=O)C1=CCC2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI Key InChIKey=YNMJLRBUCXPPSH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50409032   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409032(CHEMBL2112737)
Affinity DataIC50: 520nMAssay Description:Inhibition of Human P450 17 and NADPH-P450 reductase co-expressed in Escherichia coli with 25 uM progesteroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409032(CHEMBL2112737)
Affinity DataIC50: 170nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The Saarland

Curated by ChEMBL
LigandPNGBDBM50409032(CHEMBL2112737)
Affinity DataIC50: 1.25E+5nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 rat enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed