BDBM50408848 CHEMBL1304177

SMILES O=C(Nc1ccc(Oc2ccc(NC(=O)Nc3ccc(cc3)C#N)cc2)cc1)Nc1ccc(cc1)C#N

InChI Key InChIKey=NKTXGJQCHFJKQJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408848   

TargetInterleukin-18(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50408848(CHEMBL1304177)
Affinity DataEC50:  250nMAssay Description:Inhibition of human IL-18 expressed in Escherichia coli BL21(DE3) cells incubated for 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed