BDBM50408825 CHEMBL5280147

SMILES Oc1c(Sc2ccccc2)cc(NS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c2ccccc12

InChI Key InChIKey=ZXJHEANDHXHGMV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50408825   

TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandPNGBDBM50408825(CHEMBL5280147)
Affinity DataIC50: 700nMAssay Description:Binding affinity to STAT3 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandPNGBDBM50408825(CHEMBL5280147)
Affinity DataIC50: 800nMAssay Description:Inhibition of STAT3 phosphorylation in human HL-60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandPNGBDBM50408825(CHEMBL5280147)
Affinity DataIC50: 800nMAssay Description:Inhibition of STAT3 phosphorylation in human MOLM-13 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandPNGBDBM50408825(CHEMBL5280147)
Affinity DataIC50: 800nMAssay Description:Inhibition of STAT3 phosphorylation in human Kasumi 1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed