BDBM50408506 CHEMBL5272163

SMILES CCCCc1nc2c(N)nc3ccccc3c2s1

InChI Key InChIKey=XQXNQKAEROQGAD-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50408506   

TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50408506(CHEMBL5272163)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human TLR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50408506(CHEMBL5272163)
Affinity DataEC50:  450nMAssay Description:Agonist activity at TLR8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50408506(CHEMBL5272163)
Affinity DataEC50:  860nMAssay Description:Agonist activity at TLR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50408506(CHEMBL5272163)
Affinity DataEC50:  860nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as activation of NFkappaB by SEAP reporter gene based spectrophotometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50408506(CHEMBL5272163)
Affinity DataEC50:  410nMAssay Description:Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SEAP reporter gene based spectrophotometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50408506(CHEMBL5272163)
Affinity DataEC50:  410nMAssay Description:Agonist activity at human TLR8 stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter gene based spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed