BDBM50408286 CHEMBL2112760

SMILES C[C@H]1CN(CCCn2c3ccccc3c3ccccc23)C[C@H](C)N1C

InChI Key InChIKey=QDBZAAWPKCEIBY-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50408286   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50408286(CHEMBL2112760)
Affinity DataIC50: 244nMAssay Description:Binding affinity was evaluated using [3H]WIN-35428 binding to dopamine transporter (DAT) in rat caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50408286(CHEMBL2112760)
Affinity DataIC50: 472nMAssay Description:Inhibition of Dopamine uptake in male Sprague-Dawley rats using [3H]DA ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50408286(CHEMBL2112760)
Affinity DataIC50: 897nMAssay Description:Binding affinity was evaluated using [3H]pentazocine binding to sigma-1 receptor from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50408286(CHEMBL2112760)
Affinity DataKi:  230nMAssay Description:The compound was tested for binding affinity of Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50408286(CHEMBL2112760)
Affinity DataKi:  373nMAssay Description:Binding affinity against Serotonin transporter in male Sprague-Dawley rats using [3H]paroxetine ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50408286(CHEMBL2112760)
Affinity DataKi:  436nMAssay Description:Binding affinity Sprague-Dawley rats using [3H]WIN-35428 ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50408286(CHEMBL2112760)
Affinity DataKi:  9.37E+3nMAssay Description:The compound was tested for binding affinity nisoxatine ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed