BDBM50408203 CHEMBL4176270

SMILES CC(C)Oc1cc(ccc1NC(=O)c1[nH]c(C)c(Cl)c1Cl)C(=O)NCC(O)=O

InChI Key InChIKey=TZRVMOGDHOAVRQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50408203   

TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rat)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50408203(CHEMBL4176270)
Affinity DataIC50: 5.00E+4nMAssay Description:Antibacterial activity against Enterococcus faecalisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50408203(CHEMBL4176270)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50408203(CHEMBL4176270)
Affinity DataIC50: 47nMAssay Description:Inhibition of Escherichia coli C-terminal His6-tagged DNA gyrase B expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50408203(CHEMBL4176270)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human DNA topoisomerase 2 alpha assessed as relaxation of supercoiled plasmid pNO1 DNA incubated for 30 mins by fluorescence based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed