BDBM50407800 CHEMBL5291138

SMILES Clc1ccccc1Cn1nnc2c(Sc3nnnn3-c3ccccc3)nc(SCC#C)nc12

InChI Key InChIKey=PFBWGSSOYLFQJE-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50407800   

TargetLysine-specific histone demethylase 1A(Human)
Zhenzhou University

Curated by ChEMBL
LigandPNGBDBM50407800(CHEMBL5291138)
Affinity DataIC50: 49nMAssay Description:Inhibition of LSD1 (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhenzhou University

Curated by ChEMBL
LigandPNGBDBM50407800(CHEMBL5291138)
Affinity DataIC50: 49nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate incubated for 30 mins by Amplex Red reagent based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhenzhou University

Curated by ChEMBL
LigandPNGBDBM50407800(CHEMBL5291138)
Affinity DataKi:  16nMAssay Description:Inhibition of LSD1 (unknown origin) assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhenzhou University

Curated by ChEMBL
LigandPNGBDBM50407800(CHEMBL5291138)
Affinity DataKi:  16nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate incubated for 30 mins by Amplex Red reagent based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed